AstraZeneca(NYSE: AZT) today announced that it has received the AstraZeneca ULC's approval for its cholesterol-lowering statin Crestor.
This approval was based on its long-term safety and efficacy data. Crestor, containing rosuvastatin, is an established and widely used drug for the treatment of high cholesterol.
Crestor has been in clinical development for many years, and has received FDA approval for the treatment of Type 2 diabetes.
According to the company, Crestor has been shown to reduce triglyceride levels and increase HDL cholesterol levels in both adults and children.
The company also plans to continue its studies of the anti-hypertensive drug, Norvasc, to study its effect on blood pressure, as well as its possible cardiovascular benefits, to determine the most effective form of Crestor.
The company is committed to providing patients with the most comprehensive and effective medication management strategies for managing their cholesterol levels.
Additionally, AstraZeneca has a number of other initiatives to support patients who are experiencing the highest rates of cardiovascular disease.
About AstraZeneca
AstraZeneca is a leading global pharmaceutical company with a strong focus on the discovery, development, manufacture, and marketing of prescription and over-the-counter (OTC) pharmaceuticals. AstraZeneca is one of the world's leading pharmaceutical companies, with a proven track record in the development, manufacturing, and marketing of prescription and OTC pharmaceuticals. The company has approximately 700 employees across more than 40 countries, with a strong focus on innovation and research.
AstraZeneca's mission is to provide healthcare professionals with the information they need to make informed decisions about their patients' health and well-being. With its focus on innovation and research, AstraZeneca is committed to advancing healthcare knowledge and understanding.
AstraZeneca is a leading global pharmaceutical company with a strong focus on the discovery, development, manufacture, and marketing of prescription and OTC pharmaceuticals. AstraZeneca is one of the world's leading pharmaceutical companies, with a strong focus on innovation and research.
About AstraZeneca ULC
The AstraZeneca ULC was established in 2005 to bring together innovative pharmaceutical companies to provide an affordable, quality pharmaceutical solution to millions of people around the world. It provides access to high-quality, high-value pharmaceuticals through the development, manufacturing, and marketing of innovative pharmaceuticals. AstraZeneca ULC is dedicated to providing the world with the highest quality medicines and the highest rates of innovation, and has been part of the US pharmaceutical industry since 1987. The ULC is headquartered in New York, New York. For more information, visit: www.astrazenecabubs.com.
In 2009, AstraZeneca ULC was designated a Category IV in the US Food and Drug Administration’s (FDA) “Empowering Access to Essential Medicines.” AstraZeneca is a global company with a strong focus on the development and commercialization of essential medicines. The company has approximately 700 employees across more than 40 countries and has a strong focus on innovation and research. For more information, visit: www.astrazeneca.com.
This article was modified from the 2009 edition. More information is available at www.Crestor, like most prescription medications, is a risk with rare but serious side effects. Not every patient is at risk of these side effects, and some will experience side effects that may be hard to distinguish from the others. Fortunately, there are several ways to prevent and manage these side effects.
Here are some of the ways to prevent and manage side effects from Crestor:
It’s important to talk to your healthcare provider about all the medications, supplements, and herbal products you take. Your doctor can tell you what to avoid while you’re taking Crestor and when to contact your provider. You can also talk with your doctor about ways to lower your cholesterol and triglycerides.
There are a variety of different medications that can increase the risk of certain types of cancer. These include:
Ketoconazole ( itraconazole) is an antifungal medication that works by killing or stopping the growth of certain types of fungus. This kills the fungus and stops it from growing. Ketoconazole can also be used to treat certain types of cancer. However, like any medication, it can cause side effects and may increase the risk of cancer.
Other medications that may be taken together include:
Your healthcare provider should be able to tell you what to look for while you’re taking Crestor. Your doctor can also help you weigh the risks and benefits of different medications and combinations against the benefits of Crestor.
Certain herbal supplements may increase the risk of certain types of cancer. These supplements may include:
This combination may also increase the risk of certain types of cancer.
Certain dietary supplements may increase the risk of certain types of cancer.
These supplements may also increase the risk of certain types of cancer.
Certain types of drugs can interact with Crestor. These drugs include:
These drugs can also interact with Crestor.
Risk Summary:
Patients with cardiovascular disease (CVD) are at increased risk of sudden death from any cause. The risk of sudden death associated with treatment with rosuvastatin or Crestor has been shown to be 2.5 times greater in patients with established coronary artery disease compared to patients who are not on treatment.1,2
Crestor is a lipid-lowering medication that has been approved for treatment of LDL-C patients in the United States (U. S.) and Canada (Canada). It lowers LDL-C to approximately 50 mg/dL (the usual dose) in patients with an LDL-C level above the upper limit of normal.1,2 The risk of death from CVD is also higher in patients with coronary artery disease than in those not on treatment, with or without treatment with rosuvastatin.1-7 Therefore, there is a risk of CVD in patients treated with Crestor and Crestor-containing statin drugs, including statins, for the first time, and treatment is indicated.1
As shown inFigure 1, patients treated with Crestor had a 2.5 times higher risk of sudden death from any cause when compared to those not on treatment. This finding is important for the potential benefit of Crestor in lowering LDL-C levels in patients with CVD and for other benefits of Crestor.1
Figure 1: Risk of sudden death associated with statin treatment in patients with coronary artery disease
To evaluate the risk of sudden death from any cause in patients receiving Crestor and/or rosuvastatin, patients were divided into 3 groups: (1) those not on treatment with Crestor; (2) those who are on treatment with Crestor; and (3) those who are on treatment with Crestor. The statins were given in combination with rosuvastatin, and the patients were followed for the duration of treatment, based on the results of the clinical trials.
There was no difference in the incidence of CVD between the 3 groups, but the incidence was lower for patients on treatment with Crestor than for those on treatment with rosuvastatin.1,3 The incidence of CVD in patients treated with Crestor was also similar to that in those treated with the statins.
Figure 2: Risk of sudden death associated with statin treatment in patients with coronary artery disease
To evaluate the risk of sudden death from CVD in patients receiving Crestor and/or rosuvastatin, patients were divided into 3 groups: (1) those not on treatment with Crestor; (2) those who are on treatment with Crestor; and (3) those who are on treatment with Crestor-containing statins.
The risk of sudden death associated with statin treatment was also higher in patients treated with Crestor than in those treated with rosuvastatin.1,2
Crestor 10 mg Tablet, a part of the cholesterol-lowering drug family, is an alternative to take if your doctor tells you to stop Crestor. It contains rosuvastatin, a drug commonly used to treat high cholesterol levels. Rosuvastatin works by blocking an enzyme in the liver that synthesizes cholesterol, thereby reducing the amount of cholesterol in the bloodstream. In rare cases, Crestor can lead to liver problems, so taking rosuvastatin along with Crestor 10 mg may alleviate those symptoms.
Crestor 10 mg Tablet is a generic version of the brand-name drug Crestor. It is prescribed for the treatment of high cholesterol and certain types of cholesterol-related diseases. It comes in the form of 10mg tablets, and can be taken either alone or with other medicines to help lower cholesterol levels. One of the main benefits of Crestor 10 mg Tablet is its ability to lower LDL cholesterol, a fatty substance in our blood that carries weight. In a clinical trial, the patients taking Crestor 10 mg Tablet lost 5.6% of their cholesterol by the end of 2023. Crestor 10 mg Tablet can help reduce the risk of heart attack and stroke by lowering levels of LDL cholesterol.
Crestor 10 mg Tablet is available in various forms, including tablets, chewable tablets, and liquid formulations. You can take Crestor 10 mg Tablet as prescribed by your doctor, or as ordered by your healthcare provider. Your healthcare provider will decide on the appropriate dosage based on the severity of your cholesterol-related diseases. To make sure Crestor 10 mg Tablet is right for you, read the information on the pack before you start taking it and each time you stop taking it.
Share ShareCrestor 10 mg Tablet is a prescription medication used to lower high cholesterol levels in adults who have cardiovascular disease or have high blood pressure. It is important to inform your doctor of any other medications or supplements you are taking. Crestor 10 mg Tablet is not intended for use by children and adolescents under 12 years of age. Before taking Crestor 10 mg Tablet inform your doctor if you have liver or kidney problems, liver disease, gastrointestinal issues, a history of hereditary degenerative eye problems, or if you are allergic to rosuvastatin or any other ingredients in the pack. Crestor 10 mg Tablet is not intended for use by women and is not expected to be effective for children.
Crestor 10 mg Tablet can be taken with or without food. However, if you have any heavy or fatty foods, you should avoid taking Crestor 10 mg Tablet.
Crestor 10 mg Tablet should not be used by individuals with a known liver or kidney disease. Crestor 10 mg Tablet is not expected to be safe for use by people with high blood pressure and certain cholesterol disorders. It is also not recommended to take Crestor 10 mg Tablet in combination with another cholesterol-lowering medicine, such as atorvastatol. Additionally, Crestor 10 mg Tablet is not recommended to be used in children and adolescents due to the risk of permanent side effects and decreased heart-rate.
Before using Crestor 10 mg Tablet, inform your doctor if you have any of the following conditions:
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